Practitioner Resources

Fasting Mimicking Diet and Diabetes
Diabetic kidney disease is the leading cause of end-stage kidney complication in people with diabetes. Investigators from the Heidelberg University Hospital in Germany published a study in the Journal of Clinical Endocrinology & Metabolism showing that the fasting mimicking diet...
Growth factors, nutrient signalling, and cardiovascular ageing
Growth factors regulated by specific macro-nutrients have been shown to promote ageing and accelerate mortality in the majority of the organisms studied. In particular, the enzymes activated by growth hormone, insulin, and insulin-like growth factor-1 in mammals and their orthologs...
Growth hormone receptor deficiency is associated with a major reduction in pro-aging signaling, cancer, and diabetes in humans.
Mutations in growth signaling pathways extend life span, as well as protect against age-dependent DNA dam-age in yeast and decrease insulin resistance and cancer in mice. To test their effect in humans, we monitored for 22 years Ecuadorian individuals who...