Practitioner Resources

Guides ·
Practitioner Fasting Guide PDF
Download the fasting guide
Guides ·
Patient Brochure PDF
Download brochure
Diabetes · Diseases ·
Fasting Mimicking Diet and Diabetes
Diabetic kidney disease is the leading cause of end-stage kidney complication in people with diabetes. Investigators from the Heidelberg University Hospital in Germany published a study in the Journal of Clinical Endocrinology & Metabolism showing that the fasting mimicking diet...
Diseases ·
ProLon improves healthy skin
We have heard anecdotes about ProLon improving the skin. Now we have the science to back it up. The study suggests that fasting impacts every cell in the body including our skin. The effects of the fasting-mimicking diet on facial...
Time restricted eating ·
Fast Bar to support Time Restricted Eating (16:8 diet)
Fast Bar is similar to the L-Bar found in ProLon. It has been shown not to break the overnight fast when eaten in the morning. This may be helpful for people who want to practice a long overnight fast (time...
Metabolic syndrome ·
Fasting and Metabolic Syndrome
A systemic review and meta-analysis of randomised controlled trials found that intermittent fasting (alternate day fasting, TRF, periodic fasting, religious fasting) were associated with an improvement in cardiometabolic risk factors, including weight, waist circumference, fat mass, BMI, blood pressure, total...
Diseases ·
Fasting for Weight Loss
Low Carb versus Balanced Carbs: Same effect Debates on effective and safe diets for managing obesity and type 2 diabetes in adults are ongoing. Low-carbs diets are widely promoted as being more effective for weight loss than other diets. A...
Mechanism of action ·
Fasting, Autophagy and Neurodegenerative Diseases
Increasing evidence suggests that dysregulation of autophagy results in the accumulation of abnormal proteins and/or damaged organelles, which is commonly observed in neurodegenerative diseases, such as Alzheimer, Huntington’s, and Parkinson’s diseases  (Banerjee, Beal, and Thomas 2010). Impaired protein homeostasis and...
Diseases ·
Long COVID and Fasting
Undertaking the ProLon Fasting Mimicking Diet (FMD) during COVID has not been tested so we have no data and can therefore not recommend ProLon during an active case of COVID. Likewise, we have no data guiding a decision to abort...
About ProLon · immunotherapy ·
Fasting and Long COVID
Undertaking the ProLon Fasting Mimicking Diet (FMD) during COVID has not been tested so we have no data and can therefore not recommend ProLon during an active case of COVID. Likewise, we have no data guiding a decision to abort...
About ProLon · Longevity ·
Fasting mimicking diets (how it works and the science behind) The Sheekey Science Show
About ProLon · Guides ·
Day 6 Transition Diet
Download the handout: Day 6 Transition Diet
Cancer · Chemotherapy ·
Safety and feasibility of fasting in combination with platinum-based chemotherapy
BioMed Central 2016 Download
Diseases · Longevity ·
Association of Animal and Plant Protein Intake With All-Cause and Cause-Specific Mortality
JAMA 2016 Download
Cancer · Immunotherapy · Mechanism of action ·
Fasting-Mimicking Diet Reduces HO-1 to Promote T Cell-Mediated Tumor Cytotoxicity
Cell Press July 2016 Download
Cancer · Chemotherapy · Mechanism of action ·
Starvation, detoxification, and multi-drug resistance in cancer therapy.
The selection of chemotherapy drugs is based on the cytotoxicity to specific tumour cell types and the relatively low toxicity to normal cells and tissues. However, the toxicity to normal cells poses a major clinical challenge, particularly when malignant cells...
Cardiovascular · Cardiovascular system · Mechanism of action ·
Dietary Interventions, Cardiovascular Ageing, and Disease Animal Models and Human Studies
Recent studies indicate that dietary interventions have the potential to prevent and even treat cardiovascular disease, which is the leading cause of death. Many of these studies have focused on various animal models that are able to recreate one or...
Autoimmune disease · MS ·
A Diet Mimicking Fasting Promotes Regeneration and Reduces Autoimmunity and Multiple Sclerosis Symptoms
Download
Dementia · Mechanism of action ·
Protein restriction cycles reduce IGF-1 and phosphorylated Tau, and improve behavioural performance in an Alzheimer’s disease mouse model
In laboratory animals, calorie restriction (CR) protects against ageing, oxidative stress, and neurodegenerative pathologies. Reduced levels of growth hormone and IGF-1, which mediate some of the protective effects of CR, can also extend longevity and/or protect against age-related diseases in...
Cancer · Chemotherapy · Mechanism of action ·
Short-term calorie and protein restriction provide partial protection from chemotoxicity but do not delay glioma progression
short-term starvation (STS) protects normal cells while simultaneously sensitising malignant cells to high-dose chemotherapeutic drugs in mice and possibly patients. The fasting-dependent protection of normal cells and sensitisation of malignant cells depends, in part, on reduced levels of insulin-like growth...
Cancer · Chemotherapy · Glioblastoma · Mechanism of action ·
Fasting enhances the response of glioma to chemo and radiotherapy
Glioma, including anaplastic astrocytoma and glioblastoma multiform (GBM) are among the most commonly diagnosed malignant adult brain tumours. GBM is a highly invasive and angiogenic tumour, resulting in a 12 to 15 months median survival. The treatment of GBM is...